CLINICAL AND IMMUNOLOGICAL FEATURES OF BRONCHIAL ASTHMA IN CHILDREN UNDER THE INFLUENCE OF ATYPICAL MICROFLORA

Abstract

Today, bronchial asthma (BA) remains one of the most common chronic, inflammatory, and allergic diseases in pediatrics. According to the World Health Organization (WHO), approximately 10–15% of the pediatric population suffers from varying degrees of bronchial asthma. The development of the disease is significantly influenced by environmental factors, genetic predisposition, immune system imbalance, and various infectious agents.In recent years, the role of atypical respiratory pathogens such as Mycoplasma pneumoniae and Chlamydia pneumoniae has become increasingly evident, particularly in the worsening of asthma symptoms, shortening of remission periods, and persistence of inflammatory processes. These atypical infections exhibit tropism for bronchial epithelial cells and can induce prolonged, low-grade inflammation.