IMMUNE AND ANGIOGENIC COMPONENTS OF THE TUMOR MICROENVIRONMENT IN DISSEMINATED OVARIAN CANCER: PROGNOSTIC AND THERAPEUTIC IMPLICATIONS

Authors

  • Ulmasov F. G. Author
  • Esankulova B. S. Author
  • Davronov B. A. Samarkand Branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology Author

Keywords:

Ovarian cancer, tumor microenvironment, angiogenesis, immune escape, VEGF, PD-L1, CD8⁺ T-cells, macrophages.

Abstract

Background The tumor microenvironment (TME) plays a decisive role in the progression of epithelial ovarian cancer (EOC). Immunosuppressive cells and pro-angiogenic factors such as tumor-associated macrophages (TAMs), VEGF, and PD-L1 contribute to metastasis, chemoresistance, and poor prognosis. A better understanding of these interactions is essential for developing targeted therapies.

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Published

2025-09-23

Issue

ICEFBM- 24th SEPTEMBER 2025

Section

Articles

How to Cite

IMMUNE AND ANGIOGENIC COMPONENTS OF THE TUMOR MICROENVIRONMENT IN DISSEMINATED OVARIAN CANCER: PROGNOSTIC AND THERAPEUTIC IMPLICATIONS. (2025). International Conference on Economics, Finance, Banking and Management , 55-58. https://econfseries.com/index.php/6/article/view/2885