ASSESSMENT OF IMMUNE STATUS FEATURES IN CHILDREN SUFFERING FROM CHRONIC TONSILLITIS ASSOCIATED WITH CHRONIC CYTOMEGALOVIRUS INFECTION

Abstract

To date, numerous studies have shown that inflammatory diseases often progress to a chronic course, particularly when the process is localized in the palatine tonsils. The main reason for conducting this study was the high prevalence and significance of CMV (Cytomegalovirus) and EBV (Epstein-Barr Virus) infections among children. When CMV infection is congenital, it has been well studied and thoroughly described in scientific literature. Many researchers have concluded that CMV infection may contribute to the exacerbation of numerous chronic and recurrent diseases. Furthermore, it can trigger autoimmune responses in the body. The key rationale for this study was the high incidence and clinical relevance of CMV infection among children. However, the characteristics of immune status in school-aged children with active CMV infection remain insufficiently studied.